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Aralen uses: This medication is used to prevent certain types of malaria, a parasite infection, when traveling to certain areas that have malaria. Another drug may be used instead if you are going to an area with resistant malaria. Chloroquine may also be used with other medications to treat certain less severe (uncomplicated) types of malaria or a spreading infection with another parasite (ameba). Chloroquine is an amebicide and antimalarial drug. It works by killing ameba and the form of the malaria parasite that infects the red blood cells.OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.This drug may also be used to treat certain immune diseases (e.g., rheumatoid arthritis, lupus).How to use Chloroquine Phosphate OralTake this medication by mouth with or without food. If stomach upset occurs, take with a meal. For prevention of malaria, take chloroquine exactly as directed by your doctor, usually once weekly on the same day each week. Start this medication usually 1 to 2 weeks before you enter the malaria area, and continue to take it during your stay and for 4 weeks after leaving the area, or as directed by your doctor.For treatment of a sudden/severe attack of malaria, take this medication as directed, usually 4 doses over 3 days. The first dose is larger and is followed by 3 smaller doses. On day 1 take the large dose followed 6 hours later with a smaller dose, then take the next smaller doses on days 2 and 3.For treatment of ameba, take this medication as directed, usually once daily for 2 to 3 weeks. The first 2 doses are larger.If you are taking any antacid, do not take chloroquine within 4 hours before or after the antacid.Dosage is based on your body weight, medical condition, and response to treatment.It is very important to continue taking this medication exactly as prescribed by your doctor. This medication works best when taken exactly as directed. If you are taking this drug once a week, it may help to mark your calendar or travel schedule with a reminder.Do not take more or less of this drug than prescribed. Do not stop taking it before completing treatment, even if you feel better, unless directed to do so by your doctor. Skipping or changing your dose without approval from your doctor may cause prevention treatment to be ineffective, cause the amount of parasite to increase, make the infection more difficult to treat (resistant), or worsen side effects.No drug treatment is completely effective in preventing malaria. Therefore, seek immediate medical attention if you develop symptoms of malaria (e.g., fever, chills, headache, other flu-like symptoms), especially for 2 months after completing this prescription.It is important to prevent mosquito bites (e.g., using appropriate insect repellents, wearing clothes that cover most of the body, remaining in air-conditioned or well-screened areas, using mosquito nets, using insect-killing spray). Buy insect repellent before traveling. The most effective insect repellents contain diethyltoluamide (DEET). Ask your doctor or pharmacist to recommend the appropriate strengths of mosquito repellent for you/your children.Chloroquine Phosphate Oral is used to treat the following:Infection by Amebae that is Not in the Intestines, Malaria caused by the Protozoa Plasmodium Falciparum, Prevention of Falciparum Malaria, Malaria caused by the Protozoa Plasmodium Vivax, Preventive Treatment of Vivax Malaria, Malaria, Malaria PreventionChloroquine Phosphate Oral may also be used to treat:Infection of the Liver due to Amebae, Increased Calcium in the Blood from Sarcoidosis, Porphyria Cutanea Tarda, Chronic Inflammation of Blood Vessels in the Skin, Skin Allergy to Sunlight, Disease that Causes Disc-Shaped Patches On the Upper Body, Systemic Lupus Erythematosus, Rheumatoid Arthritis, Joint Inflammatory Disease in Children and Young Adults